Systemic Lupus Erythematosus - An Overview Term Paper by scribbler

A discussion about the systemic lupus erythematosus.
# 152037 | 1,243 words | 5 sources | APA | 2012 | US
Published on Nov 16, 2012 in Medical and Health (Medical Studies) , Medical and Health (Pharmacy)

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This paper describes Systemic Lupus Erythematosus, commonly known as Lupus, which is a chronic autoimmune disorder that affects approximately 1.5 million Americans. The paper includes a brief overview of Lupus along with a discussion about new therapeutic developments and experimental treatments. Additionally, the paper notes how a diagnosis of Lupus is made. Next, the paper examines various new treatments for Lupus, such as bone marrow stem cells replacement. Finally, the paper highlights several studies that offer new hope about potential treatments for this condition. The paper concludes by stating thatstem cell based therapy would offer the cure for Systemic Lupus Erythematosus.


Systemic Lupus Erythematosus
Diagnosis of Lupus
Treatment for Lupus
Stem Cell Replacement

From the Paper:

"There is no known cure for Lupus. However, the symptoms of Lupus can be appropriately treated to reduce the inflammation and to control the damage to other vital organs of the body. For most Lupus patients, anti-inflammatory drugs are the mainstay treatment and are enough to effectively manage their inflammation symptoms. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) such as ibuprofen, naproxen, etc are also very effective in controlling joint inflammation and related pain. Frequently these anti-inflammatory drugs are taken along with a dose of anti ulcer drugs such as misoprostol (Cytotec(r)), omeprazole (Prilosec(r)), lanzoprazole (Prevacid(r)), to balance any stomach related side effects. Besides these, corticosteroids such as Prednisone and methyl-prednisolone and immunosupressants such as Rheumatrex , Azathioprine, Cytoxan ,etc are also prescribed to control the hyper active immune system observed in Lupus patients. [LFA] This combination of immunosuppressive/immunomodulatory treatments shows significant improvements in most patients. Drug-induced morbidity is a cause for concern. Researchers are currently exploring more effective and less toxic therapies. The use of stem cells for treating Lupus is one such therapy under intense research. In particular, the potential of autologous hematopoietic stem cell transplantation (HSCT) is being studied vigorously."

Sample of Sources Used:

  • NIH, 'Systemic Lupus Erythematosus', Accessed Mar 15th 2010, Available at
  • LFA, 'Lupus Diagnosis', Accessed mar 15th 2010, available at,
  • Richard K Burt, MD; Ann Traynor MD & Laisvyde MD (Feb 2006), 'Nonmyeloablative Hematopoietic Stem Cell Transplantation for Systemic Lupus Erythematosus', Accessed Mar 15th 2010, available online at,
  • Amanda Widtfeldt, Jan 31, 2006, 'Life Threatening Lupus Responds to Stem cell Transplant Therapy', Accessed Mar 15th 2010, Available at,
  • Lingyun Sun, Kentaro Akiyama, & Huayong Zhang (June 2009), 'Mesenchymal Stem Cell Transplantation Reverses Multi-Organ Dysfunction in Systemic Lupus Erythematosus Mice and Humans', Stem Cells. 27(6): 1421-1432.

Cite this Term Paper:

APA Format

Systemic Lupus Erythematosus - An Overview (2012, November 16) Retrieved May 28, 2023, from

MLA Format

"Systemic Lupus Erythematosus - An Overview" 16 November 2012. Web. 28 May. 2023. <>