Microfluidic Protein Crystallization Term Paper by Jay Writtings LLC

Microfluidic Protein Crystallization
Looks at microfluidic metering systems as a potential realistic solution to many practical chemical and biological integration obstacles.
# 119490 | 2,845 words | 21 sources | MLA | 2010 | US
Published on May 03, 2010 in Chemistry (Biochemistry) , Biology (Biotechnology) , Physics (General)

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This paper explains that microfluidic metering systems or "labs on chips" are micrometer scale devices that can perform many fluidic operations in a very short amount of time. Several properties of fluid flow and mass transport on the micrometer scale that are favorable to biological analysis, protein crystallization in particular, are described by the author. The paper concludes that the soft, durable elastomer from which these microfluidic devices are constructed allows a dense array of valves to close selectively and completely with applied pressure.

Table of Contents:
A Monolithic Microfluidic Chip
Protein Crystallization Applications

From the Paper:

"Microfluidic devices are usually constructed using bulk and surface methods to mold crystalline silicon or glass and operate by valveless, electrokinetic or pressure-driven means.While they are capable of injecting and manipulating nanoliter volumes, their performance depends strongly on the pH, ionic strength, and viscosity of the working fluid.The material from which they are fabricated is stiff with a Young's modulus of approximately 100GPa, a property that limits device size and complexity."

Sample of Sources Used:

  • Chayen, N. Trends in Biotech. 2002, 20(3), 98.
  • Krupka, H.; Rupp, B.; Segelke, B.W.; Lekin, T.P.; Wright, D.; Wu, H.C.; Todd, P.; Azarani, Arezou. Acta Cryst. 2002, D58, 1523-1526.
  • McPherson, A. Methods 2004, 34, 254-265.
  • McPherson, A. Eur. J. Biochem. 1990, 189, 1-23.
  • Cudney, B.; Patel, S. Acta Cryst. 1994, D50, 414-423.

Cite this Term Paper:

APA Format

Microfluidic Protein Crystallization (2010, May 03) Retrieved May 24, 2022, from https://www.academon.com/term-paper/microfluidic-protein-crystallization-119490/

MLA Format

"Microfluidic Protein Crystallization" 03 May 2010. Web. 24 May. 2022. <https://www.academon.com/term-paper/microfluidic-protein-crystallization-119490/>