Human Genetic Disorders in Particular Populations Research Paper

Human Genetic Disorders in Particular Populations
Looks at the origins of diseases and different theories of evolution of genetic disorders and their relationships with particular populations.
# 147666 | 3,850 words | 8 sources | MLA | 2011 | US


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Description:

This paper first explains that the genetic composition of particular populations defines various superficial differences among them as well as the predisposition to some diseases in one population and a resistance to them in others. Next, the author discusses the genetic multifactorial disorders of breast and colon cancer among Ashkenazi Jews and the single gene disorder of sickle cell anemia among individuals of African descent. The paper relates the problem of Huntington's chorea, which is caused by a chromosome abnormality, among descendants from Europeans and the single gene disorder hemochromatosis found in people from northern Europe.

Table of Contents:
Introduction
Multifactorial Disorders: Breast and Colon Cancer among Ashkenazi Jews
Prevalence of Disorders Caused by Chromosome Abnormalities: Huntington's Chorea
Single Gene Disorders: Prevalence of Sickle Cell Anemia
Single Gene Disorders: Hemochromatosis

From the Paper:

"The evidence against it demonstrated that the sickle cell trait offered survival advantage against malaria only to children before they developed a degree of acquired immunity. Most adults were able to develop antibodies that attacked the parasite, thus the sickle cell gene was of little advantage to them.
"However, the Allison's hypothesis is supported by some studies of malaria epidemics and other evidentiary materials. The most obvious fact is that sickle cell disease is more common in the regions infested with malaria parasites."

Sample of Sources Used:

  • Bloom, Mariam. Understanding Sickle Cell Disease. University Press of Mississippi, 1995.
  • Edelstein, Stuart J. The Sickled Cell From Myths to Molecules. Cambridge: Harvard University Press, 1986
  • Fergus, Kathleen and Jill Simonsen. "Breast and Ovarian Cancer in the Ashkenazi Jewish Population." Genetic Health, inc. 23 Aug. 2000: 2. 05 Dec 2010. <http://www.genetichealth.com/BROV_GEN_of_BROV_In_ASHJ.shtml>.
  • Genetic Science Learning Center. "What Are Genetic Disorders?" Learn. Genetics 5 December 2010. <http://learn.genetics.utah.edu/content/disorders/whataregd/>.
  • Kolata, Gina. "Breast Cancer Gene in One Percent of U.S. Jews." The Science Times Book of Genetics. Ed. Wade, Nicholas. New York: The Lyons Press, 1998.

Cite this Research Paper:

APA Format

Human Genetic Disorders in Particular Populations (2011, June 01) Retrieved July 12, 2020, from https://www.academon.com/research-paper/human-genetic-disorders-in-particular-populations-147666/

MLA Format

"Human Genetic Disorders in Particular Populations" 01 June 2011. Web. 12 July. 2020. <https://www.academon.com/research-paper/human-genetic-disorders-in-particular-populations-147666/>

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