Molecular Microbiology Article Review by Nicky

Molecular Microbiology
An article review of "RsaL provides quorum sensing homeostasis and functions as a global regulator of gene expression in Pseudomonas aeruginosa" by Rampioni, Giordano, Martin Schuster, Everett Peter Greenberg, Iris Bertani, Marco Grasso, Vittorio Venturi.
# 146852 | 1,078 words | 1 source | MLA | 2011 | US
Published on Jan 19, 2011 in Biology (Molecular and Cell) , Biology (Genetics) , Chemistry (General)


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Description:

In this article, the writer reviews an article by Rampioni et al., entitled "RsaL provides quorum sensing homeostasis and functions as a global regulator of gene expression in Pseudomonas aeruginosa", regarding one of the most virulent and antibiotic resistant pathogens that is Pseudomonas aeruginosa. The writer maintains that the authors realize the importance of controlling this pathogen and have targeted quorum sensing as a primary first line defense in regulating this bacteria's virulent growth rate and debilitating effect in human beings. The writer discusses that the results of the study are certainly promising and they have opened up the understanding of quorum sensing activity in organism to greater levels and revealed even more complexity than previously thought. The writer concludes that this alone is enough to promote much further study into both quorum sensing and the activity of the molecule Rsal on that function.

Outline:
Introduction
Methods
Results
Discussion

From the Paper:

"The authors realize the importance of controlling this pathogen and have targeted quorum sensing as a primary first line defense in regulating this bacteria's virulent growth rate and debilitating effect in human beings. Quorum sensing can be compared to a social behavior determinant which helps to regulate the overall population density of the bacterial community of Pseudomonas aeruginosa. In effect it is the controlling mechanism that senses the environment around the bacteria and starts or stops a population explosion of the pathogen. Finding the key chemical in the molecules of this genetic trigger is of primary concern tot he authors. Using Molecular microbiological techniques to control the gene expression may be far more effective that simple antibiotic treatments, which bacterial strains can become immune to over time in just a few generations of the population."

Sample of Sources Used:

  • Rampioni, Giordano, Martin Schuster, Everett Peter Greenberg, Iris Bertani, Marco Grasso, Vittorio Venturi, Elisabetta Zennaro, & Livia Leoni. "RsaL provides quorum sensing homeostasis and functions as a global regulator of gene expression in Pseudomonas aeruginosa". Molecular Microbiology. (2007) 66.6 1557-1565

Cite this Article Review:

APA Format

Molecular Microbiology (2011, January 19) Retrieved September 29, 2022, from https://www.academon.com/article-review/molecular-microbiology-146852/

MLA Format

"Molecular Microbiology" 19 January 2011. Web. 29 September. 2022. <https://www.academon.com/article-review/molecular-microbiology-146852/>

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