Papers on "Insights into the Localization of 'mRNA'" and similar term paper topics

Paper #007757 :: Insights into the Localization of 'mRNA'
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A review on an article discussing the insights into the localization of 'mRNA' in embryonic and differentiated mammalian cells as it pertains to how proteins that 'mRNA' code for are localized, modified and expressed.

Written in 2001; 1,910 words; 14 sources; MLA; $ 60.95

Paper Summary:

This paper reveals the increasing importance of 'mRNA' study in understanding protein synthesis, localization and expression. It discusses the cellular mechanisms and techniques for measuring them. The writer explores the observed effects on development to the differentiation of the most complex cells and concludes that 'mRNA' localization has proven to be a highly conserved and important mechanism in the cell.

From the Paper:

"When cells are dividing and differentiating into tissues and higher complex structures, each tissue-type cell is uniquely characterized by the membrane bound and cytoplasmic proteins it contains. These various proteins are sequestered within the cell by various mechanisms. The details associated with protein targeting have been the focus of considerable research in the last decade. As a result, a good deal is known about protein sorting signals and the machinery needed for endo and exocytosis as well as the mechanisms for transporting vesicles along microtubules and actin filaments within the cytoplasm. However, less is known about how cytosolic proteins are parceled out within the cytoplasm. It has become increasingly clear that the transport and localization of mRNA, not the proteins alone, plays an important role in the localization of proteins. mRNA localization is an active process highly conserved from a simple Drosophilia oocyte model to a very complex mammalian neuron. It allows for specificity in development and function that would otherwise not be possible."

Tags: molecular interactions transport mechanism simple oocyte complex differentiated cells neuron

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