Papers on "T- Cell B-Cell Collaborations in the Immune System" and similar term paper topics
Paper #006457 ::
T- Cell B-Cell Collaborations in the Immune System
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A descriptive overview of the vertebrate adaptive immune response to both intra and extra-cellular pathogens with explicit focus on T-cell B-cell collaboration and antibody response.
Written in 2001; 1,425 words; 9 sources; APA;
$ 47.95
Paper Summary:
This paper covers the major pathways by which foreign antigens are identified and dealt with through the adaptive immune response which is paramount on B-cell and T-cell responses and interaction with one another in distinct pathways and steps. It includes several diagrams and their explanations of antigens, B-Cells, T-Cells, APC's and more and their interactions and processes they go through.
From the Paper:
"All immune responses involving T-cell B-cell collaborations follow distinct pathways of interactions and development. These very pathways of the adaptive immune response are almost entirely dependant on the cellular interaction of B- cells and T- cells with one another. It is within each stage of these pathways and the progression of an adaptive immune response that we will concern ourselves. The following is a condensed synopsis of the adaptive immune response and the cellular interactions that will be the emphasis of this paper. Within secondary lymph tissues foreign antigen is presented to naive B-cells via their surface immunoglobulins (Igs) receptors. The same antigen is also presented to naive T-cells at this time. This presentation and subsequent recognition of antigen by both types of cells results in and end product of proliferation and development of naive B-cells into plasma cells whose function is the production of soluble immunoglobulins (antibodies), and the differentiation and development of memory B-cells whose function is to respond to subsequent exposure to the same antigen. However, this pathway is not self-sufficient and requires the direct interaction of activated T-cells, specifically ?helper? T-cells (Th2 cells) 1,9. It is these T-cells in conjunction with the antigen presenting B-cells that interact to produce a hormonal response to infection. These interactions activate Th2 cells that in turn promote B-cell activation both through T-cell secreted cytokines, (interlukeinI1-2, 4 and 5), and also through direct cell to cell contacts involving specific surface proteins and corresponding receptors and the signaling initiated by the binding of these proteins to one another."
Tags:
B-Cell T-Cell immune system responses pathways antibody pathogens vertebrate
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