| Papers [1-5] of 5 | Search results on "CREUTZFELDT JAKOB DISEASE": |
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Creutzfeldt-Jakob Disease, 2007.
A research paper analyzing whether a factor besides the prion could be involved in Creutzfeldt-Jakob disease (CJD).
2,531 words (approx. 10.1 pages), 8 sources, APA, $ 76.95
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Abstract
This paper discusses the devastating Creutzfeldt-Jakob disease (CJD). It describes the initial symptoms of CJD and it progression throughout the illness. The paper then analyzes the link between CJD and the prion protein in the brain. It also looks at diagnosis of the disease. The paper then goes on to research if the fact that CJD is limited to the central nervous system and olfactory-nerve tissue could indicate that some other factor besides the prion is involved. The paper presents the research design, its challenges and results.
Table of Contents:
Introduction
Research Question
Methods
Research Team
Funding
Results
Leadership Skills
Challenges
Summary
From the Paper
"Very little is known about CJD in terms of what causes the mutation of the prion protein. Whereas sporadic CJD was always marked by low incidence since the 1920s, there is currently an alarming increase in the incidence of the disease in Switzerland. The reasons for this increase need to be studied immediately. After a decade of focus on the prion protein, studies are needed to determine underlying factors that may be affecting that protein to mutate. The mechanism by which the prion can avoid the immune system needs to be studied, along with the central question of how a protein can destroy neurons. The idea that a protein can destroy is a total paradox which needs to be resolved. Other questions concern how patients might be diagnosed without the need for invasive procedures."
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Mad Cow Disease, 2007.
An analysis of the epidemiology, pathophysiology and prevention for Mad Cow Disease (known as Creutzfeldt-Jakob disease in humans).
1,445 words (approx. 5.8 pages), 10 sources, MLA, $ 47.95
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Abstract
This paper discusses Mad Cow Disease, otherwise known as Bovine Spongiform Encephalopathy or as Creutzfeldt-Jakob disease in humans. It discusses the history, background and pathophysiology of the disease. It then goes on to describe prevention and treatment options for the disease, concluding that there are no effective treatments available. The paper concludes by discussing nursing and collaborative care for patients with the disease.
Table of Contents:
Epidemiology
Pathophysiology
Prevention and Treatment
Differences in Classic CJD and Variant CJD
Nursing and Collaborative Care
From the Paper
"Variant CJD has a median age at death of 28 years. The duration of the illness is approximately 13-14 months. Some of the clinical signs and symptoms include: prominent psychiatric/behavioral symptoms, painful dyesthesiasis; and delayed neurologic signs. The "Pulvinar sign" on an MRI is present in greater than 75% of most of the Variant CJD. The presence of "florid plaques" on neuropathology is usually in large numbers and easily detected. The agent is readily detected in the lymphoid tissue. There is a marked accumulation of protease-resistance prion protein noted in the brain. This is why the Variant CJD is much more easily detected because it shows up on more tests."
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Prion Disease in Humans, 2005.
An overview of Mad Cow Disease and how it has benefited the medical world.
1,636 words (approx. 6.5 pages), 5 sources, APA, $ 53.95
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Abstract
Ever since Mad Cow Disease sparked terror in international headlines, the public has been concerned about eating beef. Mad Cow Disease is not, however, the first or only prion-caused disease. Several others, including Creutzfeldt-Jakob Disease (CJD) and kuru in humans and a host of agricultural animal disorders join Mad Cow in both cause and effects, the major effect being horror. This paper argues that, while the presence on the planet of a disease that literally lays waste to human brain tissue is frightening, there are two probabilities that can be seen as reasons not to be terrified. Instead, people could be hopeful that research sparked by the publicity surrounding Mad Cow Disease will eventually bring answers to such sociologically and medically devastating diseases as Alzheimer's Disease, and other lesser known but just as deadly diseases such as Lou Gehrig's Disease. The paper shows that these two probabilities are first, that prion-caused diseases are much less prevalent than media hype would indicate and, second, that a cure or vaccination is relatively certain to be discovered in the near to medium term.
Paper Outline:
Introduction
Methods
Discussion
Conclusion
References
From the Paper
"Questions have arisen regarding why these particles are not attacked by the body's defense mechanisms, and the answer, Mahy noted, is that they are so odd, they are simply not recognized and therefore cannot be neutralized. Prions contain no nucleic acid and are therefore extremely " extremely resistant to inactivation by chemical or physical interventions that would inactivate viruses" (Mahy 1998) because there is no vector through which to deliver the 'poison'. Even more so than viruses, then, it is reasonable to wonder whether prions are, in fact, alive. And if they are not alive, then how can they infect an organism? Do they replicate like bacteria and viruses, or what?"
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Jurek Becker's "Jakob the Liar", 2002.
This paper discusses the role of the radio in Jurek Becker's "Jakob the Liar", a Holocaust novel.
690 words (approx. 2.8 pages), 1 source, $ 24.95
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Abstract
This paper describes Becker's novel "Jakob the Liar": Jakob, a Polish Jew in the Ghetto, finds himself a neighborhood hero by fabricating reports from his imaginary radio. The paper illustrate that the radio may not be real, but the impact Jakob's radio reports have on the community is real: The inhabitants of this ghetto community now have a sense of hope as they are told of "reports" that the armies are coming to save them. The paper author feels that Becker's use of the imaginary radio brings the reader into the reality of living in Jakob's ghetto.
From the Paper
"In the case of Jakob and Lina, the radio brings these two people closer together. When Jakob 'plays' the radio for Lina, it is a moment that draws them closer and one of sincere comedy. These were bleak times, and the radio essentially brings hope and happiness to a neighborhood that faces the inevitable. These moments happen often within the first half of the novel, as the radio reports are a ray of light. "
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"Macario", 2005.
Compares Roberto Galvadon's 1960 film production about a man who encounters three apparitions to the Jakob and Wilhelm Grimm tale, "Godfather Death."
954 words (approx. 3.8 pages), 2 sources, MLA, $ 33.95
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Abstract
This paper compares and contrasts the literary elements in Galvadon's movie, "Macario," and the Grimm tale, "Godfather Death". The paper looks at the similarities and differences in both stories' theme, structure, style, symbolism, and plot.
From the Paper
"Fairy tales offer rich imagery, symbolism, and archetypes on which longer, more complex works can be based. Roberto Galvadon's 1960 film Macario is one of those works, an enchanting black-and-white Mexican production that shares several structural elements in common with the Jakob and Wilhelm Grimm tale "Godfather Death." In the movie and the fairy tale, a destitute man with a large family encounters three apparitions: God, the Devil, and Death. He ignores the first two on principle: the Devil because he is a trickster and God because he permits the rich to feed off the poor; but the man embraces Death as a friend because the Grim Reaper takes the lives of the rich and the poor. In return, Death offers the man a magical healing potion that restores life to the dying. In order to use it properly, however, the man must follow specific instructions."
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