Abstract
This paper proposes a study to determine whether a mechanism exists that links C-1 esterase inhibitor deficiency with Chronic Fatigue syndrome (CFS). FS is a clinically defined condition which is characterized by severe and disabling fatigue. It examines the problems faced by health care professionals in treating CFS patients since the etiology of the illness is not known. It attempts to determine whether CFS patients are characterized by a C-1 esterase inhibitor deficiency and whether replacement therapy for C-1 esterase inhibitor deficiency leads to improvements in patients' CFS status. It also looks at the significance of the study to nursing since advanced practice nurses play an important role in the delivery of care to CFS patients.

Outline
Introductory Statement
Statement of the Problem
Research Questions
Significance of the Study to Nursing
Background Information
Review of Literature
C-1 Esterase Inhibitor Deficiency: Related Research
Chronic Fatigue Syndrome (CFS)
Conclusions Relevant to the Study Problem

From the Paper
"The role of the advanced practice nurse practitioner continues to expand. In the contemporary period, some of the more prominent of the roles performed by the advanced practice nurse practitioner are as follows: the role of the nurse practitioner as a care provider; the role of the nurse practitioner as a manager; the role of the nurse practitioner as a patient health educator; the role of the nurse practitioner as a consultant; the role of the nurse practitioner as a researcher; and the role of the nurse practitioner in relation to psychiatric and metal health nursing."

Tags:manager, nurse, fatigue, mental, health

Abstract
Cites need for study re: biochemical mechanisms involved in CFS. Contends research is lacking in identifying the mechanisms that cause CFS. Extensive literature review covers severe & disabling fatigue & impact on daily functioning. Discusses symptoms of condition including sleep disturbances, pain, short-term memory loss, depression. Possible causes & characterizations of CFS. Conceptual framework. Research questions. Hypotheses. Research procedures & data analysis testing.

From the Paper
"Introduction
Chronic fatigue syndrome (CFS) is a clinically defined condition which is characterized by severe and disabling fatigue. This fatigue is accompanied by a combination of symptoms that typically include self-reported impairments in concentration and short-term memory, sleep disturbances, and musculoskeletal pain (Evengard, Schacterle & Komaroff, 1999; Wilson, Hickie, Lloyd & Wakefield, 1996).
CFS prevalence rates in the United States are estimated at a minimum of 4 to 10 cases per 100,000 adults 18 years of age or older (Fukuda & Gantz, 1995). In one U.S. study (Evengard et al., 1999), the prevalence among medical patients was found to be about 1%. A several-fold higher prevalence rate of self-reported..."

Abstract
The paper examines the stock prices of Allstate (ALL), CF Industries Holdings (CF) and Dell (DELL) and assesses the effect of the subprime mortgage crisis on these three companies. The paper also predicts the future direction of these companies and their markets.

From the Paper
"Allstate (ALL) started two months ago at $46.19 per share, and now sits at $29.51. ALL's price was stable until the beginning of October, at which point it began a hard slide to its current point. It traded as low as $26.96 on October 10th,and has seen a slight rebound since that time.
"The major factor affecting the performance of ALL stock in the past two months has been the performance of the market, and the risk concerning the financial sector in general. The decline in ALL over the past two months is equivalent to a decline of 36.1%. In that span, the Dow has declined 17.09%. Given that the beta of ALL is 1.11, the expected decline in ALL given that Dow decline would have been 18.97%. Therefore, ALL have moved more than expected. The Dow Jones Financial Services Titans Index has dropped 32.2% in the same time frame, so it would appear that much of Allstate's troubles are sector-related."

Tags:shares, investors, subprime, mortgage, crisis, market

Abstract
The paper shows that the field of pediatric nursing is a particularly large one in which its members may find themselves having to counsel both young patients and their families suffering from a myriad of diseases. Cystic fibrosis (CF), in particular, is a debilitating disease that strikes many young people. The paper discusses how, in the first years following its discovery, many children could not expect to make it to their teen years. Today, with advances in the management and care of this disease, patients are living into their 40s and it is even possible that there will one day be a cure. This paper will look at CF from a historical perspective. The timeline of its discovery and research are briefly presented, as are a few of the significant "milestones" in the history of the treatment of CF and what these mean for people battling this disease.

From the Paper
"Perhaps the most exciting advent in the history of the treatment of CF, as well as the most controversial, is the use of gene therapy. The idea behind gene therapy is to treat an illness by addressing and correcting its genetic cause. With the identification of the gene that actually causes CF, noting that it is a defect of sorts in the gene that causes the disease, it was only a matter of time before gene therapy was applied to CF. In 2000, an advanced experiment was performed in North Carolina. The idea was to give patients currently suffering from CF a healthy gene and hope that it will fix what is wrong with the unhealthy gene, even replace it, thereby curing the patient. Results and future applications of this procedure remain to be seen."

Tags:Dorothy, Andersen, protein, di, Sant-Agnese, pancreatic, enzymes

Abstract
This paper examines cystic fibrosis (CF), which is an autosomal recessive disease that involves not only the pulmonary system, but also affects other organ systems. The writer explains that the pathogenesis of CF is caused by a genetic mutation on the long arm of Chromosome 7, specifically a mutation on the cystic fibrosis transmembrane regulator, or CFTR gene. This paper discusses treatment, complications and nursing interventions that need special attention in adolescents.

From the Paper
"Cystic fibrosis is an inherited disease that affects 1/3700 infants in the U.S. alone (Green, Grosse, Earley & Mei, 2005). It is a disease that predominantly affects individuals of Caucasian decent. It is a disease that can be screened for early on right after birth; however, the median age at which it is diagnosed is 14.5 months without newborn screening (median age for disease detection 0.5 months)...."

Tags:nursing, cystic fibrosis

Abstract
This research paper discusses the anatomy and physiology of the cystic fibrosis (CF). The paper discusses the imaging modalities and the unique tool represented in the MRI, as well as its drawbacks. The paper also discusses the drawbacks of the other imaging modalities and the future of imaging technology in the diagnosis and treatments of CF. The paper contains figures.

Table of Contents:
Literature Review
Chapter One
Diagnosis and the Anatomy and Physiology of a Life Threatening Disease: Cystic Fibrosis
What Science Looks For
A Complex Physiology
Chapter Two
Computerized, Tomography as a Tool in Treatment Approach for Cystic Fibrosis
Chapter Three
MRI and Cystic Fibrosis
Chapter Four
The Drawbacks of Modern Technology
Chapter Five
Discussion and Conclusion

From the Paper
"Genetic research today, more than anything else, is probably the most aggressive and advanced it has ever been before. It raises ethical and social issues in many circles, and those issues deserve debate and there is a need to ensure ethical practices when words like "cloning" and human genetic engineering are being used (Howie, 2002, p. 139). However, these ongoing discussions of ethics should not prohibit or bring to an end research that is going to ease the pain and suffering of children and young adults, and improve their quality of life and longevity with less pain."

Tags:pathology, genetics, lungs, radiology, imaging

Abstract
The paper looks at a personal and informal account of chronic fatigue syndrome (CFS) and of fibromyalgia (FM). The paper discusses how CFS and FM are similar conditions since both involve pain and fatigue and also result in misunderstanding from outsiders. The paper shows how the individual's account of her and her husband's illness agrees with the literature.

Outline:
Introduction
Discussion of CFS
Critical Analysis
Conclusion

From the Paper
"Based on Zona's account, CFS means total exhaustion and complete lack of energy. She can accomplish just a little at a time and must be careful of her limits. She experiences many aches and pains as well as spasms which cause insomnia. She has numerous allergies especially to medications. Food also is a problem for allergies. She feels as though her brain is fogged and she is difficulties concentrating. She also has problems with vision and refocusing. Dry throat and acid burn are other problems. She does not experience the same set of symptoms each day. Sometimes her symptoms are similar to a panic attack."

Tags:aches, pains, tiredness, insomnia, symptoms, productivity

Abstract
This paper is a research proposal to assess the effects on Chronic Fatigue Syndrome patients of increases in the serum levels of C-1 esterace inhibitor within the context of the concept of complement dis-regulation. This paper states that Chronic Fatigue Syndrome (CFS) is a clinically defined condition that is characterized by severe and disabling fatigue, but there is no validated diagnosis or treatment that will lead to a cure for CFS. The author will use Beck Depression Inventory (BDI) Kohlman Evaluation of Living Skills (KELS) and The Fatigue Inventory as the psychological measurements.

From the Paper
"Clinical anxiety is defined within the context of feelings experienced by a person. At one level, anxiety is defined as a feeling of mingled dread and apprehension about a person's future where no specific cause for such dread and apprehension is present. At another level, anxiety is defined as a chronic feeling of fear by a person. This feeling may be mild in intensity or the feeling fear may be overwhelming for the person so affected. Anxiety also may be a secondary drive involving an acquired avoidance response. In this latter context, when in the presence of the conditioning stimulus, a person will display behavior that may be interpreted as evidence of the presence of anxiety. "

Tags:measurement, inventory, treatment, diagnosis, disregulation

Abstract
This paper discusses the hereditary lung disease, cystic fibrosis (CF). The paper presents statistics of those suffering from CF in the United States. The cause, symptoms and diagnosis of the disease are examined. The paper explores the prognosis for CF patients and analyzes the available treatments. The paper contends that although much progress has been made in recent years in terms of diagnosis, treatment, quality of life, as well as average life spans, there is clearly much more to be done.

Outline
Introduction: What is Cystic Fibrosis?
Incidence and Etiology
Pathology and Pathophysiology
Signs, Symptoms and Complications
Diagnosis
Prognosis
Treatment
Clinical Trials and Studies
Hidden Benefits
Conclusion

From the Paper
"Cystic fibrosis is a serious genetically inherited disease that is estimated to affect around 30,000 children and adults in the United States alone (CFF, 2005). In this disease, a defective gene causes parts of the body to produce abnormal sticky, thick mucus. This abnormal mucus causes the lungs to become clogged, and can also lead to serious lung infections that can be fatal (2005). In addition to the negative effect on lung function, the thick mucus also causes an obstructive barrier to the pancreas which results in the patient having difficulty with food digestion as well as nutrient absorption. Cystic Fibrosis can cause complications leading to early mortality (the average age of the Cystic Fibrosis patient today is 30). Yet advances in treatment have steadily increased life the life expectancy of people suffering from this disease."

Tags:pancreas, mucous, respiratory

Abstract
This paper discusses nursing management of cystic fibrosis (CF). It begins by describing the pathophysiology of the disease and the risk factors associated with it. The paper then looks at complications that may arise with the disease and possible treatment options that are available. Finally, the paper discusses the overall nursing management of CF.

Table of Contents:
Introduction
Pathophysiology
Risk Factors
Treatment
Complications
Nursing Management

From the Paper
"Some of the many complications that may arise in CF patients are pulmonary in nature. Apart from pneumonia, a host of pulmonary complications such as atelectasis, pneumothorax, hemoptysis, allergic aspergillosis, hypertrophic osteoarthropathy, acute respiratory failure and chronic respiratory failure may result during the natural history of CF (Boat, 1998). Salt depletion can also occur in CF patients, particularly during warm weather and activity where sweat is excessively excreted. Gastrointestinal complications, including those of the hepatobiliary tree include intestinal obstruction, liver disease, pancreatitis and hyperglycemia may also occur and are treated accordingly."

Tags:respiratory failure, pulmonary chest autosomal recessive