Paxil

Paper Summary:

The paper describes the history and neural mechanisms of Paxil, the brand name of an orally administered psychotropic drug, Paroxetine hydrochloride. The paper discusses the drug's efficacy for the treatment of certain mental disorders, including the most severe form of post-menopausal syndrome (PMS). The paper identifies the adverse effects of this drug and relates that it can induce suicidal tendencies. The paper also discusses the use of Paxil by children and young adults.

Outline:
History and Neural Mechanisms
Uses and Efficacy
Adverse Effects

From the Paper:

"Paxil is the brand name of an orally administered psychotropic drug, Paroxetine hydrochloride, manufactured by Glaxo Smith Kline (GlaxoSmithKline 2007). The effectiveness of paroxetine in treating major depressive disorder, social anxiety disorder, obsessive compulsive disorder, panic disorder, generalized anxiety disorder and posttraumatic stress disorder has been the focus of studies, which linked the chemical combination to central nervous system activities involved in the disorders. These studies showed that sufficient doses of the drug block neuronal uptake of serotonin into human platelets. Animal studies also suggested that paroxetine strongly and selectively inhibit reuptake and has negligible allergic, sedative and cardiovascular effects as do other psychotropic drugs (GlaxoSmithKline)."

Sample of Sources Used:

• Carey, B. and Harris, G. (2006). Antidepressant may raise young adult suicide risk. 2 pages. The New York Times: The New York Times Company
• GlaxoSmithKline (2007). How Paxil Works. Your Life is Waiting. 1 web page. Retrieved on November 27, 2007 from http://www.paxilcr.com/how_paxilcr_works/how_paxilcr_works.html
• ----------------------------. Paxil Prescribing Information. 42 pages.
• Healthfacts (2002). Paxil risky for kids - warning issued. 2 pages. Center for Medical Consumer, Inc. : Gale Group
• Nursing (2003). Approved to Treat the Severest Form of PMS, Paxil CR may also cool hot flashes. 2 pages. Springhouse Corporation: ProQuest Information and Learning Company

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