Lowering LDL Cholesterol Levels

Paper Summary:

This paper tests the hypothesis if the blood levels of individuals with genetically linked hypercholesterolemia, who have already had their LDL cholesterol lowered by this latter drug therapy, will see increased results if Xenical is added to their drug regime. The author points out that the research will be conducted on 100 male and 100 female because men and women have historically been shown to react differently to a range of medications. The paper states that, because the subjects are randomly selected, and the subject pool is a relatively large one, this quantitative study should be generalizable beyond this particular group of individuals. Questionnaire included.

Table of Contents
Introduction
Literature Review
Methodology
Rights of Human Subjects
Null Hypothesis
Limitations of the Study

From the Paper:

"Before discussing the specific hypothesis that this research is designed to test, it will be useful to define some of the key terms that are being used in this research. To understand why high levels of bad cholesterol are indeed bad it is important to understand the basic chemistry of the substances involved. Lipids may be characterized as the "building blocks" of the fats (or some related fatty substances) that are found in living organisms (both plants and animals). In animals, lipids, which serve as sources of energy for the individual, are composed mostly of cholesterol; and riglycerides; a form of protein called lipoproteins; and phospholipids, which are molecules comprised of phosphoric acid, along with nitrogen and fatty acids. Lipoproteins can be divided into five different types, arranged by both their size and density; they are also commonly divided by whether they carry cholesterol or triglycerides. Those lipoproteins that carry cholesterol are themselves commonly referred to as cholesterol."

More papers on Lowering LDL Cholesterol Levels:

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• Term Paper # 125638 : "Causes of High Cholesterol"
• Research Paper # 67026 : "ATP III Guidelines for Treating Cholesterol"

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