This paper is a research proposal to study the relationship of Gastroesophageal Reflux Disease (GERD) to Esophageal Adenocarcinoma, secondary to Barrett's Syndrome.
Written in 2005; 5,170 words; 27 sources; APA; $ 129.95
Paper Summary:
This paper explains that gastroesophageal reflux disease (GERD) is a common condition, which may result in esophagitis caused by the esophagus repeatedly being exposed to acid from the stomach. The author points out that the preliminary literature review provides ample evidence that a relationship exists between the progression of Barrett's Esophagus to Adenocarcinoma and a patient history of GERD; however, the exact parameters of this relationship have not yet been fully recognized and there is still much debate with regard to whether or not GERD should be defined as a true risk factor for progression to advanced adenocarcinoma. The paper relates that the population sample will be male patients, age 50 years, with a positive diagnosis of cancer; the GSRS questionnaire will be the survey instrument to assess the extent to which patients recall experiencing GERD symptoms prior to the onset of their disease and the extent to which each patient sought out care for symptoms of GERD prior to their diagnosis of adenocarcinoma.
Table of Contents
Introduction
Background/Significance of Study
Conceptual Framework
Literature Review
Background of GERD/Barrett's Esophagus
Correlation of GERD to Barrett's and Adenocarcinoma in Patients
Risk Factors for Barrett's Progression to Esophageal Adenocarcinoma
Control of GERD and Adenocarcinoma
Summary of Literature Available
Methods
Sample/Settings
Instrument
Data Collection Procedure
Limitations
Population Sample
Data Analysis
Appendix A - Consent Form
Appendix B - Demographic Data Sheet
Appendix C - Questionnaire
From the Paper:
"The questionnaire is noted for offering a comprehensive evaluation of patient symptoms related to GERD. The reliability and validity of the Gastrointestinal Symptom Rating Scale has been evaluated in patients with GERD; study results reveal that the GSRS is a useful patient-rated symptom scale for evaluating patients and outcomes for treatment with GERD; the scale is shown to have good reliability and construct validity, and the GSRS scales are capable of discriminating GERD symptom severity accurately. The scale is interview based and consists of 15 items that assess gastrointestinal symptoms. The GSRS have a seven graded Likert Type scale that can be used for analysis, where 1 is equivalent to lack of symptoms and 7 is indicative of severe symptoms."
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