An examination of the prion hypothesis and the five known transmissible spongiform encephalopathies (TSE) diseases in humans.
Written in 2009; 1,315 words; 7 sources; APA; $ 44.95
Paper Summary:
This paper examines transmissible spongiform encephalopathies (TSEs) which are fatal, incurable degenerative diseases of the brain transmitted by prions. The paper explains the prion hypothesis, disease transmission and features of TSE and then examines each of the five known TSE diseases in humans. Lastly, the paper looks at the research regarding a possible cure or vaccine for TSE.
Table of Contents:
The Prion Hypothesis
Disease transmission
Disease markers
Features of TSE
Kuru
Creutzfeldt-Jakob disease
Gerstmann Straussler Scheinker syndrome
Fatal familial insomnia
Alper's syndrome
Possible cure or vaccine for TSE
From the Paper:
"There is progressive cerebellar dysfunction in the middle years. There is unsteadiness, clumsiness, incoordination and progressive gait difficulty. The cerebellar signs become more severe as the disease progresses with ataxia, dysarthria, and nystagmus. Additional findings in some are, parkinsonism, pyramidal and extrapyramidal findings, blindness and gaze palsies. Compared to CJD, dementia and myoclonus are either absent or minor."
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