Reduction of Subcutaneous Fat

Paper Summary:

The paper discusses how, although a majority of research studies promote the use of phosphatidylcholine solubilized with deoxycholate for the reduction of subcutaneous fat, there are others that question its use due to the inability to determine the active ingredient. The paper provides a literature review and concludes that there is a serious lack of clinical evidence to support the efficacy or safety of the treatment. The paper is of the opinion that use of this compound could have dire consequences for patients and doctors alike.

Outline:
Abstract
Introduction
Literature Review
Methods
Research Synthesis
Discussion
Conclusion
Acknowledgments

From the Paper:

"The search for a shapely body has led medical science to search for treatments that will provide the fastest results, with the least effort. Mesotherapy was developed in Europe and has become a popular method for containing unwanted fat deposits in the body. The treatment is beginning to spark interest in the United States as well. Mesotherapy to remove fat is cost effective as compared to liposuction and does not require the healing time. Mesotherapy costs between $1,000 to $6,000, as compared to liposuction that costs between $3,00 -$12,000 (Strauss, no date)."

Sample of Sources Used:

• Atoba MA, Ayoola EA, Ogunseyinde O. Effects of essential phospholipid choline on the course of acute hepatitis-B infection. Trop Gastroenterol. 1985; 6:96-9.
• Bechara FG, Sand M, Altmeyer P et al. Intralesional lipolysis with phosphatidylcholine for the treatment of lipomas: pilot study. Arch Dermatol. 2006 Aug;142(8):1069-70. Retrieved March 24, 2007 from http://www.hubmed.org/display.cgi?uids=16924064.
• Hanin I, Ansell GB, eds. Lecithin. Technological, Biological and Therapeutic Aspects. New York and London: Plenum Press; 1987.
• Doris Hexsel "Phosphatidylcholine in the treatment of localized fat". Journal of Drugs in Dermatology. Oct 2003. FindArticles.com. Retrieved March 24, 2007 from http://www.findarticles.com/p/articles/mi_m0PDG/is_5_2/ai_110220257
• Hexsel, D., Serra, M., Mazzuco, R., Dal'Forna, T., and Zechmeister, D. (2003). Phosphatidylcholine in the treatment of localized fat. Journal of Drugs in Dermatology, October, 2003,

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