Pharmacological Treatment for Paraphilias

Paper Summary:

This paper examines the mechanisms of three pharmacological agents (MPA, CPA, and LHRH agonists) for paraphilias and their effectiveness as well as an overview of paraphilias. It explains that the high rate of overlap among paraphilias suggests that the cause of various types of paraphilias might be the same. MPA, CPA and LHRH agonists appear to be very effective although they do not cure paraphilias. Ethical issues of pharmacological approaches (chemical castration) and a discussion about methodology of studies for these drugs are also provided.

From the Paper:

"People in the United States have been increasingly interested in pharmacological treatment of paraphilias or sexually deviant behaviors especially since several states passed so-called "chemical castration laws," following the case of Kansas v. Hendricks in 1997. These laws are capable of allowing or even requiring sexual offenders to be treated with medication in order to reduce their urges to commit sexual offenses (Bradford & McDonald, 2000). In the United States, only medroxyprogesterone acetate (MPA) is currently approved as treatment for sex offenders, while cyproterone acetate (CPA) is mainly used in Western Europe (Bradford & McDonald, 2000; Gijs & Gooren, 1996; Keagan, 2001; Nelson, 2000). In fact, these two drugs are primarily used to treat atypical sexual behaviors that are often considered to be attributed from paraphilias (Bradford & McDonald, 2000; Nelson, 2000; Oltmanns & Emery, 2001; Seligman & Hardenburg, 2000). Furthermore, some other drugs such as specific serotonin reuptake inhibitors (SSRIs) and luteinizing hormone-releasing hormone (LHRH) agonists have drown researchers' attention as promising pharmacological therapeutic agents for paraphilias (Bradford & McDonald, 2000; Keegan, 2001;)."

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