This paper discusses a research report on "Periodontal Disease and Prematurity among Non-smoking Sri Lankan Women" by P.S. Rajapakse, M. Nagarathne, K.B. Chandrasekra, and A.P. Dasanayake.
Written in 2007; 1,898 words; 6 sources; APA; $ 60.95
Paper Summary:
In this article, the writer examines the research in the article "Periodontal Disease and Prematurity among Non-smoking Sri Lankan Women". The writer discusses the hypothesis that periodontal disease has a role in causing preterm low birth weight deliveries among rural primi-gravida women who are free of tobacco, alcohol, and drug use. The writer notes that various factors have been associated with the delivery of preterm and low-birth weight infants and the role of infection is receiving increasing attention. The writer concludes that the data and statistics presented link periodontal disease as one of the contributing factors for preterm low birth weight deliveries. Further, the writer maintains that this study can educate mothers that even if they feel they are perfectly healthy and free from smoking, alcohol consumption, and drug use, they are not guaranteed to have a term infant with normal weight.
From the Paper:
"Periodontal disease is associated with a chronic Gram-negative infection of the periodontal tissues which results in long-term local elevation of pro-inflammatory prostaglandins and cytokines and an increase in the systemic levels of some of these inflammatory mediators. Hence, periodontal disease has the potential to influence preterm low birth weight through an indirect mechanism involving inflammatory mediators or a direct bacterial assault on the amnion which is suggested in this study conducted in Matale, Sri Lanka. 227 subjects were studied, resulting in a cohort of 66 subjects with the exposure and 161 without the exposure. In this study, the authors observed a higher proportion of preterm low birth weight among subjects with higher pocket depths, plaque, and bleeding scores (the exposed group). This can be linked to a series of animal and clinical studies by Offenbacher and co-investigators that indicate an association between periodontal infection and adverse pregnancy outcome."
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