Galactosemia

Paper Summary:

This paper examines the disorder known as galactosemia. It discusses the signs and symptoms of the disorder and the diagnostic investigations that can be used to make a diagnosis. The paper then examines possible management options for the disorder, particularly long-term management. The paper includes appendices of minimal galactose diets and galactose alternatives.

Table of Contents:
Introduction
Symptoms and Signs
Diagnostic Investigations
Management
Long-term Management
Conclusion
Appendix

From the Paper:

"A major cause of the late complications has been attributed to endogenous production of galactose, amounting to 1 gram per day in adults. The daily allowance of galactose during long-term treatment is also controversial. In Europe, many metabolic centers, recommend a very strict diet, with restriction of galactose containing fruits and vegetables, which make the life of patients with galactosemia very complicated. Other metabolic centers, like those in the UK, practice a more liberal approach, and advise a lactose-free diet."

Sample of Sources Used:

• Acosta, PB, Gross, KC (1995). Hidden sources of galactose in the environment. Eur J Pediatr. 1995; 154(7 Suppl 2):87-92.
• Bosch, AM, Ijlst, L, Oostheim, W, Mulders, J, Bakke,r HD, Wijburg, FA, Wanders RJ, and Waterham HR (2005). Hum Mutat. 2005; 25(5): 502.
• Bosch, AM, Bakker, HD, de B Wenniger-Prick, LJ, Wanders, RJ and Wijburg, FA (2004). High tolerance for oral galactose in classical galactosemia: dietary implications. Archives of Disease in Childhood 2004;89:1034-1036.
• Fomon, SJ & Ziegler, EE (1992). Isolated soy protein in infant feeding. New Protein Foods in Human Health: Nutrition, Prevention, and Therapy, 1992. CRC Press Boca Raton, FL.
• Fielden, MR, Samy, SM, Chou, KC & Zacharewski, TR (2003). Effect of human dietary exposure levels of genistein during gestation and lactation on long-term reproductive development and sperm quality in mice. Food Chem. Toxicol. 41:447-454.

More papers on Galactosemia:

• Term Paper # 134312 : "Newborn Medical Screening"

APA Citation:

MLA Citation: