Depression

Paper Summary:

Depression is often assuaged by a change in circumstances or a visual, olfactory, or gustatory stimulus. This essay identifies the underlying neurobiological and clinical causes of depression, especially, chronic depression. It also explores the medications that either have been used in the past or are currently in use. It also considers other factors that cause depression, such as sociological concerns, adverse reactions to drugs, and an emotional crisis.

From the Paper:

"Non-neuronal hormones are also implicated in depression. This is associated with an increased level of the hormone cortisol that is secreted by the adrenal glands located near the kidneys. Cortisol levels have been shown to decrease when the symptoms of depression go away. Even cortisol secretion finds its origin in the brain. The hypothalamic region in the brain makes corticotrophic-releasing hormone. This then stimulates the pituitary gland to release adrenocorticotrophic hormone. The next step in this pathway is the secretion of higher (than necessary) levels of cortisol. (Mackin & Allan H. Young, 2004)."

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