Comparative Evolution of the Globulin Genes

Paper Summary:

This study provides relevant background on the various globulin genes in general and the gamma globulin gene in particular. The paper aims to determine how this family of globulin genes has changed over time in various organisms, as well as describe where the globulin genes can be found and their functions.

Table of Contents:
Introduction
Review and Discussion
Background and Overview
Globulin Gene Evolution
Evolution of Globulin Genes
Conclusion

From the Paper:

"Since the pioneering work of Cohn and others, researchers have since shown that globulins represent an important source of protein in seed plants and they are found in relatively small amounts in various cereals; in addition, globulins are also found in animal fluids are enzymes, antibodies, and fibrous and contractile proteins typically contained in the blood plasma (Haurowitz, 2006). As noted above, to date, three types of globulin have been identified--alpha, beta, and gamma; alpha and beta globulins are transport proteins, serve as substrates upon which other substances are formed, and perform other diverse functions. In addition, the gamma globulins play a vital role in natural and acquired immunity to infection (Haurowitz, 2006)."

Sample of Sources Used:

• Achord, J. L. Understanding hepatitis. Jackson, MS: University Press of Mississippi, 2002.
• Boyer, S. H. Papers on human genetics. Englewood Cliffs, NJ: Prentice-Hall, 1963.
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• De Chadarevian, S., & Kamminga, H. Molecularizing biology and medicine: New practices and alliances, 1910s-1970s. Amsterdam: Harwood Academic, 1998.
• Emes, R. D., Beatson, S. A., Ponting, C. P., & Goodstadt, L. Evolution and comparative genomics of odorant- and pheromone-associated genes in rodents, 2004, Genome Research, 14:591-602.

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