Chronic Fatigue Syndrome ( CFS)

Paper Summary:

Cites need for study re: biochemical mechanisms involved in CFS. Contends research is lacking in identifying the mechanisms that cause CFS. Extensive literature review covers severe & disabling fatigue & impact on daily functioning. Discusses symptoms of condition including sleep disturbances, pain, short-term memory loss, depression. Possible causes & characterizations of CFS. Conceptual framework. Research questions. Hypotheses. Research procedures & data analysis testing.

From the Paper:

"Introduction
Chronic fatigue syndrome (CFS) is a clinically defined condition which is characterized by severe and disabling fatigue. This fatigue is accompanied by a combination of symptoms that typically include self-reported impairments in concentration and short-term memory, sleep disturbances, and musculoskeletal pain (Evengard, Schacterle & Komaroff, 1999; Wilson, Hickie, Lloyd & Wakefield, 1996).
CFS prevalence rates in the United States are estimated at a minimum of 4 to 10 cases per 100,000 adults 18 years of age or older (Fukuda & Gantz, 1995). In one U.S. study (Evengard et al., 1999), the prevalence among medical patients was found to be about 1%. A several-fold higher prevalence rate of self-reported..."

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