Bioinformatics Search Engine

Paper Summary:

This paper describes a recent initiative of the The National Center for Biotechnology Information, which is a national resource for molecular biology information. The project is known as Western Washington University Periodic Search Agent for Protein Database Information or WWU Search Agent. This web-based search engine browses and does periodic searches of the protein databases of the National Center for Biotechnology Information (NCBI) using the Basic Local Alignment Search Tool or BLAST. The writer describes the benefits of this project, which include its interfacing with the NCBI BLAST and the continuous updates and enhancements done by NCBI on the system.

Includes Charts:

Chart - Content of Protein Sequence Databases
Fig. 1 - General Subsequence and Database Input Area
Figure 2 - Options for Advanced BLASTing Input Area
Figure 3 - Format input area for report outputs

From the Paper:

"The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches. BLAST can be used to infer functional and evolutionary relationships between sequences as well as help identify members of gene families. The summary of the Content of Protein Sequence Databases with the sequences they contain are as follows: (NCBI, 2006)"

Sample of Sources Used:

• Chandhok, Saurabh. Western Washington University Periodic Search Agent for Protein Database Information. 2006. 20 June 2006. <http://www.saurabhchandhok.com/blast/>.
• National Center for Biotechnology Information (NCBI). Basic Local Alignment Search Tool (BLAST). 25 April 2006. 20 June 2006. <http://www.ncbi.nlm.nih.gov/blast/>.

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