Toxoplasmosis

Paper Summary:

This paper discusses a form of toxoplasmosis caused by a microscopic parasite called toxoplasma gondii, found in all warm-blooded animals like pets, livestock and human beings. It explains that the disease is transmitted from a mother contaminated with toxoplasma at the time of pregnancy to unborn child; eating under-cooked or uncooked meat of infected animals or eating food, drinking water or inhaling contaminated dust. The author points out that pregnant women can become infected by swallowing cat feces from a toxoplasma-infected cat; therefore, pregnant women should not empty the litter-box of cats. The paper relates that medication of opportunistic infections (OIs) like toxoplasmosis needs some intricate trial-and-error to determine the best treatment for an individual patient.

From the Paper:

"The cure of toxoplasmic retinochoroiditis intends killing free Toxoplasma organisms before they can attack host cells, as well as the encysted parasite, without aggravating the situation as an effect. Folate synthesis inhibitors, mainly pyrimethamine and sulphadiazine, have been most regularly used to cure all groups of patient with toxoplasmic retinochoroiditis. These, and the protein biosynthesis inhibitor clindamycin, are useful against the extra-cystic form of Toxoplasma. Instantaneous treatment at the beginning of symptoms is a logical approach to therapy. This could lessen the probability of re-invasion by Toxoplasma of other host cells, and the extent of disease process, as well as the possibility of ensuing extension and reappearance. Systemic corticosteroids are also widely used in the healing of vigorous incidents of toxoplasmic retinochoroiditis. Treatment with glucocorticoids, including progesterone, can restrain antimicrobial activity of macrophages, and thus may have an effect on the result of steroid therapy for ocular toxoplasmosis."

More papers on Toxoplasmosis:

• Essay # 42174 : "Toxoplasma Gondii"

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