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The Biochemistry of Lead Poisoning
Essay # 50495
The Biochemistry of Lead Poisoning
A look at the chemical mechanisms and biological effects of lead poisoning.
1,395 words (approx. 5.6 pages) |
9 sources |
MLA | 2003
Paper Summary:
This paper describes lead poisoning, focusing on the chemical processes that take place as lead (II) displaces zinc (II) from ALAD and inhibits hemoglobin synthesis. The technical details of the inorganic and biochemical processes at play are explored and discussed, as well as the mechanisms of various lead poisoning therapeutic strategies. This paper also contains several referenced illustrations and figures.From the Paper:
"The protein ALAD, also know as porphobilinogen, is crucial in heme biosynthesis (2). ALAD, a ZnII metalloenzyme, consists of A and B subunits each of which contain a zinc atom when functional. The functionality of the A and B sites has been determined experimentally by displacement of zinc. When magnesium displaces zinc at the A site ALAD is marginally active. Furthermore, when magnesium replaces the zinc in the B site no change in the activity of the enzyme is observed (3). Thus the A site is key to the activity of the enzyme. However, when PbII displaces the active ZnII ion present in the A- site, the enzyme is rendered useless."More papers on The Biochemistry of Lead Poisoning:
Cite this paper
APA Citation:
The Biochemistry of Lead Poisoning (2012, January 15). Retrieved February 13, 2012, from http://www.academon.com/Essay-The-Biochemistry-of-Lead-Poisoning/50495
MLA Citation:
"The Biochemistry of Lead Poisoning" 15 January 2012. Web. 13 Feb. 2012. <http://www.academon.com/Essay-The-Biochemistry-of-Lead-Poisoning/50495>
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CMode
Publisher Since:
May 11, 2003 I attended a highly-selective liberal arts college in the East, and now am in medical school. As an undergraduate I was a chemistry major, but due to the extensive general education requirements at my school, I have written papers in a number of subjects. All of the papers submitted received a grade of at least A-, and should serve as excellent resources. I scored 800s on both my verbal SAT I and the writing SAT II, as well as a 13-15 on the verbal reasoning section of the MCAT.
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