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T- Cell B-Cell Collaborations in the Immune System


# 6457
T- Cell B-Cell Collaborations in the Immune System
A descriptive overview of the vertebrate adaptive immune response to both intra and extra-cellular pathogens with explicit focus on T-cell B-cell collaboration and antibody response.
1,425 words (approx. 5.7 pages) | 9 sources | APA | 2001 United States


Paper Summary:

This paper covers the major pathways by which foreign antigens are identified and dealt with through the adaptive immune response which is paramount on B-cell and T-cell responses and interaction with one another in distinct pathways and steps. It includes several diagrams and their explanations of antigens, B-Cells, T-Cells, APC's and more and their interactions and processes they go through.

From the Paper:

"All immune responses involving T-cell B-cell collaborations follow distinct pathways of interactions and development. These very pathways of the adaptive immune response are almost entirely dependant on the cellular interaction of B- cells and T- cells with one another. It is within each stage of these pathways and the progression of an adaptive immune response that we will concern ourselves. The following is a condensed synopsis of the adaptive immune response and the cellular interactions that will be the emphasis of this paper. Within secondary lymph tissues foreign antigen is presented to naive B-cells via their surface immunoglobulins (Igs) receptors. The same antigen is also presented to naive T-cells at this time. This presentation and subsequent recognition of antigen by both types of cells results in and end product of proliferation and development of naive B-cells into plasma cells whose function is the production of soluble immunoglobulins (antibodies), and the differentiation and development of memory B-cells whose function is to respond to subsequent exposure to the same antigen. However, this pathway is not self-sufficient and requires the direct interaction of activated T-cells, specifically "helper" T-cells (Th2 cells) 1,9. It is these T-cells in conjunction with the antigen presenting B-cells that interact to produce a hormonal response to infection. These interactions activate Th2 cells that in turn promote B-cell activation both through T-cell secreted cytokines, (interlukeinI1-2, 4 and 5), and also through direct cell to cell contacts involving specific surface proteins and corresponding receptors and the signaling initiated by the binding of these proteins to one another."

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APA Citation:

T- Cell B-Cell Collaborations in the Immune System (2012, January 15). Retrieved February 10, 2012, from http://www.academon.com/Essay-T-Cell-B-Cell-Collaborations-in-the-Immune-System/6457

MLA Citation:

"T- Cell B-Cell Collaborations in the Immune System" 15 January 2012. Web. 10 Feb. 2012. <http://www.academon.com/Essay-T-Cell-B-Cell-Collaborations-in-the-Immune-System/6457>




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Published by:

Ickball US
Publisher Since:
Jul 30, 2002
I attend the university of Redlands in Redlands CA. It is a small private college with a foundation in liberal arts offering major in a wide verity of studies. I am part of an interdisciplinary honors program and I also created my own major focusing in both biological science and chemistry coupled with studies in Sociology, Anthropology and Archaeology. Upon completion of this program I will have the equivalent of both a B.A. in biology and a B.A. in Sociology and plan on attending Medical school. Above all I take the up most pride in my literary work and I hope that it can aid others in their own work and understanding.
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