Sickle Cell Retinopathy

Paper Summary:

This paper discusses sickle cell disease, a genetic disorder that manifests itself in all body systems. Although some authors have questioned whether retinopathy is actually a sickle cell trait, ocular manifestations may be severe, including sudden blindness. The paper discusses the surgical treatment that is indicated once retinopathy advances to the proliferative stage and contends that several treatment options may be utilized, but should be chosen to meet the patient's medical history and disease severity.

From the Paper:

"Sickle cell hemoglobinopathy encompasses a group of inherited genetic disorders, which cause erythrocytes to sickle and adversely affect multiple organ systems. The sickled erythrocytes lead to microvascular occlusion, which affects the peripheral retinal vasculature and results in retinal ischemia and development of proliferative sickle cell retinopathy. If this series of events does not stabilize or reverse, the end-stage results may be retinal infarction and/or detachment 1."

More papers on Sickle Cell Retinopathy:

• Term Paper # 142982 : "The Biology of Sickle Cell Disease"
• Term Paper # 142981 : "Anatomical Aspects of Sickle Cell Disease"
• Research Paper # 72544 : "Sickle Cell Pain Management"

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