Prions: Proteinaceous Infectious Particles

Paper Summary:

This paper explains what prions are and how degenerative brain diseases result from abnormal prions. The paper discusses professor Stanley Prusiner's discovery of prions and pediatrician Carleton Gajdusek's contributions to this discovery, as well as the prion diseases themselves. Additionally, the paper explains the infectious nature of the prion protein and explains the progression of prion diseases and tests used to diagnosis the disease.

From the Paper:

"Recent cases of Mad Cow Disease have focused the public attention on prion diseases and the small proteins that are believed to cause them. The scientific community has been slow to recognize this mechanism of disease, since prion-caused encephalopathies can demonstrate diverse symptoms, and share characteristics with other disorders, such as dementia."

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