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age, assessment, effect, hearing, loss, mice, old, onset, presbyacusis, prevention, psychosocial, research, scientific, unaware
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Essay (General) # 66043 :: Presbyacusis
This paper examines scientific and psychosocial research about the prevention and effect of presbyacusis, old age onset hearing loss.
Written in 4; 1,320 words; 2005 sources; MLA; $ 44.95
Paper Summary:
This paper explains that the majority of people will experience hearing loss to greater or lesser extent as they get older because, with aging, the inner ear (cochlea) containing nerve cells, which convert sound into nervous impulses that are sent to the brain, don't work as well and eventually begin to degenerate. The author points out that most people do not go completely deaf and the severity of the hearing loss varies from person to person of the same age. The paper examines some research projects, whose apparent success might provide hope that one day hearing loss will no longer be associated with old age and can be reversed; another study describes the psychosocial consequences of hearing loss, which indicated that the majority of the people with presbyacusis did not report many quality of life distractions besides the inability to listen to the music. Glossary.
From the Paper:
"Research was conducted by using senescence-accelerated mice (SAM) that develop progressive hearing loss at an early age. Mice were irradiated with 9Gy and later injected with 4x10 bone marrow cells from 2-month-old mice. After three months, the auditory brainstem response (ABR) was measured in order to evaluate the progress of hearing loss. It was noted that mice showed age-related hearing impairment above 2000Hz. After ABR and splenectomy five mice from experimental and control group were subject to further procedures, involving "intracardiac perfusion with saline followed by periodate-lysin-paraform aldehyde fixation and decalcification at 4 degrees C .in 5% buffered ethylene diaminetetra-acetate for seven days." The results showed that the immune system in mice was reconstituted by the donor cells and the age-related impairment of T-cell function is corrected. The age-related auditory response is also ameliorated after the manipulations."

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