Physiology Of Pressure/Altitude

Paper Summary:

This paper examines the physiological changes that occur in the body at high altitude, particularly in respect to the heart. The paper examines what happens to the body during short-term exposure and long-term exposure to high altitude, and exposure to extremely high altitudes.

From the Paper:

"Several circulatory changes mediated by stimulation of the carotid body which causes activation of the sympathetic nervous system are stimulated by short-term altitude exposure less than three or four days. These changes occur within a few minutes of altitude exposure and are related to a transient epinephrine secretion combined with a more sustained secretion of norepinephrine. These cause immediate changes which include an increase in ventilation, increased heart rate, increased cardiac output and an elevation of blood pressure. There is also an increase in coronary blood flow."

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