An examination of the causes and possible treatments for male factor infertility.
Written in 2000; 6,549 words; 58 sources; MLA; $ 150.95
Paper Summary:
This paper examines how male factor infertility is a serious medical condition that can be induced even before the child is born. This means that during pregnancy any exposure to harmful compounds will result in alteration of the developing reproductive system, which may cause permanent damage to the fertility of the male child. It looks at how both the environment and genetics are involved and how once the cause of infertility has been established, treatment is often available that will correct the condition and restore fertility. It also discusses how recently there has been an intense interest in how the environment affects male fertility, especially compounds that disrupt the endocrinology of the reproductive tract.
Outline
Abstract
Fertility
Male Factor Infertility
Impairment of Spermatogenesis
Genetic Causes of Impaired Spermatogenesis
Non-Endocrine Causes of Impaired Spermatogenesis
Varicocele
Infection
Nutrition
Defects in Sperm Transport
Retrograde Ejaculation
Impotence
Oral Treatment
Recent Advances
Conclusion
Reference List
From the Paper:
"The normal process of spermatogenesis results in the production of the spermatozoan. The process involves a series of mitotic divisions of spermatogonial stem cells, two meiotic divisions by spermatocytes, extensive morphological remodelling of spermatids during spermiogenesis and the release of free cells into the lumen of the seminiferous tubules by spermiation. The specialised structural features of the spermatozoan are a reflection of its unique functional activities. The acrosome contains enzymes essential fertilization and the flagellum contains the energy sources and machinery necessary to produce motility. The roles of these components are to ensure the delivery of the genetic material contained in the sperm nucleus to the egg, where combination of the haploid male and female pronuclei occurs, resulting in a zygote."
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