Hemophilia

Paper Summary:

This paper studies the medical disorder called hemophilia, including definition, causes, symptoms and treatment. The paper shows that due to blood's inability to clot properly, the hemophiliac is vulnerable to a number of problems caused by excessive bleeding. The paper examines different types of hemophilia, ways to determine if a child is hemophiliac and how it restricts a person's life. The paper also discusses the future of hemophilia with the advent of better technology and medical research.

From the Paper:

"Other researchers have been working on gene therapy for type B hemophilia. This has also showed promising early results (Jancin, 2000). They also used genetic coding, this time to produce factor IX. Again they used a virus to introduce a properly functioning gene. In this application of gene therapy, the goal is to cause muscle tissue to produce and release the needed clotting factor in large enough amounts to prevent bleeds (Jancin, 2000). Studies were done with mice and dogs before trying it with humans.
Researchers of course proceed cautiously with such research, and in the case of Factor IX, the researchers introduced such a small amount into patients that they expected no increase in the clotting factor. However, two of the three patients showed a significant rise in Factor IX at a clinically significant level: they had reduced need for intravenously provided clotting factor during the next year (Jancin, 2000)."

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