Discusses several dominantly inherited disorders. Huntington's Disease. Cavernous Angioma. Von Willebrand disease. How the defective genes are inherited. Genetic linkage analysis. Population and gender affected. Symptoms. Onset of disease. Mean age. Importance of genetic screening. Effect on pregnancy and the fetus. Major signs. Technical analysis of subject.
From the Paper:
"Offspring inherit one set of chromosomes from the mother and one from the father. Dominantly inherited genetic disorders are those in which only one copy of the gene for that disease is needed for the disease to be present (Robinson, 1999). The gene can be inherited from either parent, and any parent with that gene will also have the disease. A parent with such a gene has a 50 percent chance of passing it on to their offspring. One example of a dominantly inherited disease is Huntington's disease. The disease is caused by a defect on chromosome 4 in the gene for a protein known as Huntington, whose function is currently unknown (Berkow, Beers and Fletcher, 1997; Robinson, 1999). The defect in the gene causes a repeat of 40 or more copies of a combination of the C, A and G DNA..."
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