An analysis of G protein-linked receptors in communication between cells.
Written in 2004; 3,973 words; 16 sources; MLA; $ 107.95
Paper Summary:
This paper analyzes the fundamentals of the large and complex body of information already collected and still in progress on the subject of G protein-linked receptors. The paper highlights the basic nature of G protein-linked signaling and explains how physiological regulation occurs through particular mechanisms.
From the Paper:
"Cells in multi-cellular organisms, like animals, need to communicate among themselves in directing and regulating growth, development and organization (Altruis Biomedical Network 2003). Such communication modes include secreting chemicals that signal to distant cells, display cell surface chemicals that influence other cells in direct physical contact, and directly through porous cellular points called gap junctions (Altruis Biomedical Network). Endocrine signaling demonstrates the first mode, wherein hormones are secreted in the bloodstream to distant target cells. Paracrine signaling illustrates the second mode, wherein local chemical mediators are secreted and act only on cells in the proximate environment. And synaptic signaling exhibits the third mode, wherein molecules are released by vesicles at those junctions called synapses. The molecules are neurotransmitters that spread out and act only on the postsynaptic target cell (Altruis Biomedical Network). Protein receptor molecules that are on or within the target cells bind to the hormone, paracrine or neurotransmitter and a response results, depending on the speed and selectivity of the delivered signal."
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