Discusses the relationship of depression to congestive heart failure (CHF) .
Written in 2009; 805 words; 3 sources; APA; $ 28.95
Paper Summary:
This paper discusses how nonadherence to treatment regimens due to depression is the most well-documented mechanism by which depression produces adverse outcomes in coronary artery disease. The paper then explains what is meant by congestive heart failure (CHF). Next, the paper sites research into cytokines in terms of understanding disease and brain-body integration and interaction in depression and heart failure.
From the Paper:
"It is reported that cytokines impact upon the nervous and endocrine system effectively shut the circuit between the immune system and brain giving rise to the indication that neural-immune interactions are bidirectional. IL-1 and IL-6 exert potent enhancing effects on the HPA axis by stimulating hypothalamic corticotropin-releasing hormone (CRH), which is capable of activating the neuroendocrine cascade, resulting in increased pituitary adrenocorticotropic hormone and glucocorticoid release."
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