Discovery, process, history, techniques, properties, side effects.
Written in 1996; 2,250 words; 11 sources; $ 79.95
From the Paper:
"Peptides were first synthesized around the turn of the century. During the following decades, the compounds found many applications. At present, both solid and liquid phase methods may be used to chemically formulate peptides. The formation of a peptide bond requires both activation and protection. Although these processes have a long history, researchers continue to search for better coupling reagents and improved protecting group strategies.
Curtius (1881) and Fischer (1902) were the first to synthesize simple peptide derivatives (2:1-8). About that time, Hofmeister (1902) and Fischer (1906) additionally recognized that proteins actually consist of amino acids linked together by amide bonds. Subsequent peptide research generally involved the..."
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