Cataracts and the Use of Prednisone

Paper Summary:

The strong association between the use of prednisone and the subsequent development of cataracts is widely established. This paper provides a brief review of cataracts; discusses the evolution of corticosteroids and prednisone use, benefits and risks; and focuses on the interaction between cataracts and prednisone. Discussion centers on type of administration and dose dependency relative to the development of cataracts.

From the Paper:

"The World Health Organization (WHO) proclaimed cataract, on a global basis, to be the primary cause of blindness. 20.5 million individuals in the United States are affected by cataracts (Shoemaker, 2002). According to the Mayo Clinic, cataract formation affects approximately 50% of all Americans aged 65 or older ("Cataracts," 2004). At a cost to Medicare of $3.4 billion per year for cataract treatment coupled with the anticipated doubling of those with vision disturbances projected within the next thirty years (Shoemaker, 2002), cataract development and related causes are an important issue. In particular, there is a strong association between the use of prednisone and the development of cataracts."

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