A look at the anatomic features, structure, function, discovery and causes and effects of abnormalities.
Written in 1994; 1,575 words; 14 sources; $ 55.95
From the Paper:
"The Blood-Brain Barrier
The blood-brain barrier (BBB) principally consists of the interface between the blood and the brain's extracellular fluid. Evidence for such a barrier was first observed over 100 years ago. As with other physiologic phenomena, the BBB's structure and function are intimately related. The different anatomic features of the barrier give rise to its selective permeability. In the normal state, this "modified tight epithelium" provides an element of control over the brain's ambient environment. Furthermore, blood-brain barrier dysfunction may be an important etiological factor in a number of neurologic diseases.
Perhaps the first scientific researcher to document the occurrence of a blood-brain barrier was Paul Ehrlich (1885, 1906) (10:1). He observed that intravenous injection of water-soluble..."
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