A critical review of a research article examining the brain regions which are affected in Alzheimer's Disease.
Written in 2002; 4,299 words; 47 sources; MLA; $ 113.95
Paper Summary:
This paper examines the research article "Cerebrospinal Fluid Beta-Amyloid(1-42) in Alzheimer Disease: Differences Between Early- and Late-Onset Alzheimer disease and Stability During the Course of Disease" by Teipel, Hampel, Pietrini, Alexander, Horwitz, Daley, Moller, Schapiro and Rapoport (1999) which investigates region-specific corpus callosum atrophy in relation to the pattern of cortical glucose metabolism in Alzheimer. It shows how the reviewed material examines the authors' primary research questions, their justification for the study, the general methods and main findings. The review ends with a statement of whether confidence can be placed in the findings.
From the Paper:
"Methods involved a two-group comparison of AD patients (N=12) and healthy controls (N=15). It is noted that controls were volunteers but no mention is made of how any of the subjects were recruited into the study. Further, AD patients were not authenticated as having the disease; rather it was noted that some patients were suspected of "possibly" having the condition while others were viewed as "probably" having AD. Tests of cognitive functioning were administered to the AD patients showing that they ranged in degree of dementia from mild to severe."
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