Alopecia

Paper Summary:

Alopecia areata is a systemic hair loss disorder, which affects roughly around 4.7 million people in the United States alone. The paper explains that it is characterized as an autoimmune disease that leads to either localized or complete hair loss. The effects of the disease may either be permanent or reversible depending on the nature and extent of damage to the hair follicles. It is believed that both genetic as well as environmental factors have an influence in the onset of the condition. This paper provides a brief overview of the different types of alopecia and discusses in detail the possible pathophysiology and the treatment options for the disease.

Introduction
Alopecia (Different Types)
Hair Follicles (Complex Morphognesis)
Androgenic Alopecia
Molecular Pathology of AGA
Immunology of Alopecia Areata
Microcirculation in Scalp Tissues
Treatment for Alopecia (Cortisones and Anti Inflammatory and Immunotherapy Drugs)
Cosmetic Surgery
Conclusion

From the Paper:

"Alopecia is a disease triggered by the immune response of the body, which attacks and alters the normal development cycle of the hair follicles. Normally each hair follicle is in any one of the following three stages of life cycle namely anagen (growth phase), catagen (regression phase) and telogen (resting phase). Alopecia areata refers to the significant hair loss observed due to the immune response against the hair follicles in the anagen stage, resulting in severe reduction or complete stoppage of the hair growth phase. When the hair loss is observed throughout the body it is called as alopecia universalis. When complete hair loss is confined to the head, the condition is referred to as Alopecia totalis while hair loss that is localized and observed as patchy bald regions is known as Alopecia areata. [Ralph Paus]"

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