Vater

Paper Summary:

This paper discusses the diagnosis, treatment and short and long-term prognosis of VATER. The paper relates that, in order to assess VATER, one first needs to understand why this condition is named VATER. VATER stands for V(Vertebral Anomalies--where half of the vertebra is formed or the bones are abnormally small), A (Anal defects, such as anal atresia or imperforate anus), TE (Tracheo-Esophageal Defects--Esophageal atresia with tracheo-esophageal fistula), R (Renal defects--a single umbilical artery, which might be associated with urinary defects), L (Limb Defects--absence or displaced digits or fused digits). The paper concludes that it will be likely be a while before the root cause of VATER-the genes (one or more) are identified.



Outline:
Definition , Age the Disease/Condition is Diagnosed
Diagnosis of VATER
Treatment and Prognosis

From the Paper:

"Based on the symptoms that VATER association presents, it would appear that treatment modalities would involve intensive and corrective, and perhaps, repeated or simultaneous, surgery. One of the concepts that are used in the treatment of VATER is combined surgery. This involves a team of surgeons who perform the surgeries simultaneously. A study on three patients illustrates this treatment method. A ten month old boy underwent surgery of the left aortic arch as well as esophagogastronomy for esophageal atresia. The second patient a 15 day old girl also underwent a cardiac procedure and additional surgery to shift the diaphragm. An eight month old boy underwent surgery to repair an atrial septal defect and also surgery of the trachea. All surgeries were successful and the prognosis based on follow up testing was good. (Yamashiro et al., 2007)"

Sample of Sources Used:

• Al Kaissi, A., Ben Chehida, F., Safi, H., Nassib, N., Ben Ghachem, M., Gharbi, H., et al. (2006). Progressive congenital torticollis in VATER association syndrome. Spine, 31(12), E376-378.
• DeFoor, W., Minevich, E., McEnery, P., Tackett, L., Reeves, D., & Sheldon, C. (2003). Lower urinary tract reconstruction is safe and effective in children with end stage renal disease. Journal of Urology, 170(2), 1497-1500.
• Fiore, A. C., Brown, J. W., Weber, T. R., & Turrentine, M. W. (2005). Surgical treatment of pulmonary artery sling and tracheal stenosis. Ann Thorac Surg, 79(1), 38-46; discussion 38-46.
• Fujishiro, E., Suzuki, Y., Sato, T., Kondo, S., Miyachi, M., & Suzumori, K. (2004). Characteristic findings for diagnosis of baby complicated with both the VACTERL association and duodenal atresia Fetal Diagnostic Therapy, 19(2), 134-137.
• Guerrier, D., Mouchel, T., Pasquier, L., & Pellerin, I. (2006). The Mayer-Rokitansky-Kuster-Hauser syndrome (congenital absence of uterus and vagina)--phenotypic manifestations and genetic approaches. J Negat Results Biomed, 5, 1.

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