A description of mutagens and their effects on DNA, focusing on Glyoxal.
Written in 2009; 1,075 words; 9 sources; MLA; $ 37.95
Paper Summary:
This paper discusses mutagens, which are the agents of change outside the normal spectrum of DNA mutation. The writer explains that some types of mutagen damage can be linked to cancer, and these particular mutagens are also called carcinogens, though not all mutagens are so classified. The mutagen Glyoxal, which appears much more frequently within the body than other oxygen related products, and its known causes and effects, are described in detail.
From the Paper:
"Mutagens which are called "Base Altering" are kinds which cause changes in DNA base chemicals. Many of these substances imitate the DNA strands, for example causing cytosine to mutate and resemble thymine. These imitations cause the other pair of the imitated base to be taken up, rather than the pair of the mutated gene. In the example given above, an adenine would link with the pseudo-thymine and be taken up, rather than the guanine. Such a mutation would alter the DNA strand from: ATCG to ATTA, in this instance."
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