Examine literature investigating multiple organ dysfunction syndrome (MODS).
Written in 2009; 835 words; 5 sources; APA; $ 29.95
Paper Summary:
This paper describes life-threatening multiple organ dysfunction syndrome (MODS), which affects physiological systems that are not traditionally considered organs including the hematologic, the immune and endocrine systems. The author indicates that the origin of MODS might be an overwhelming, uncontrolled systemic inflammatory response activated by a number of hostile stimuli including sepsis, hypovolemic shock and severe trauma resulting in massive tissue injury. The paper reviews literature on the subject and concludes that MODS is very poorly understood.
From the Paper:
"Five systems are responsible for the inflammatory response including the systems as follows: (1) platelets; (2) endothelial cells; (3) leucocytes; (4) plasmatic hemocoagulation system; and (5) complement. Symptoms of local inflammation include: (1) rubor; (2) calor; (3) tumor; (4) dolor; and (5) function laesa. The degree of reversibility of secondary MODS is stated to be influenced by the following: (1) necrotic tissue damage; (2) changes in vessel wall caused by proinflammtory cytokines; (3) during chronic process - proliferation of less valuable cells; and (4) apoptosis."
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