Alzheimer's Disease

Paper Summary:

The paper discusses the physiology, incidence, genetics, treatment, demographics and other factors affecting persons suffering with Alzheimer's. The paper highlights the manner in which the affliction affects persons with regard to behavioral problems, psychotic symptoms as well as depression. The paper then discusses the management of the problem and comments on how treatment with drugs can be effective.

From the Paper:

"In the medical treatment of Alzheimer's disease, two aspects are concerned. First is the delaying or improvement of the patient's cognitive abilities. The second aspect is the medical treatment of psychiatric and behavioral disturbances. In improving the patient's memory and cognitive abilities, the pathogenesis of the disease must be considered. "There is a lack of acetylcholine being secreted by the brain cells. Therefore, the volume of acetylcholine must be amplified by blocking acetyl cholinesterase action. Acetyl cholinesterase is responsible in the enzymatic breakdown of acetylcholine after a synapse has occurred. Several acetyl cholinesterase inhibitors are approved for Alzheimer's disease. "

Sample of Sources Used:

• Alzheimer's Disease Education and Referral Center. (2006). Alzheimer's disease fact sheet, NIH Publication No. 06-3431. http://www.nia.nih.gov/Alzheimers/Publications/adfact.htm.
• Braunwald, E., Fauci, A. S., Kasper, D. L., Hauser, S. L, Longo, D. L. & Jameson, J. L (Eds.). (2002). Harrison's 15th edition: Principles of internal medicine. New York: McGraw-Hill Companies, Inc.
• Cummings, J.L, Frank, J. C., Cherry, D., Kohatsu, N.D., Kemp, B., & Hewett, L. (2002). "Guidelines for managing Alzheimer's disease: Part I. Assessment." American Family Physician, 65(11), 2263-2272.
• Cummings, J.L, Frank, J. C., Cherry, D., Kohatsu, N.D., Kemp, B., & Hewett, L. (2002). "Guidelines for managing Alzheimer's disease: Part II. Treatment." American Family Physician, 65(12), 2525-22534.
• Cummings, J.L. (2004). "Alzheimer's disease." New England Journal of Medicine, 351, 56-67.

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• Research Paper # 92033 : "Alzheimer's Disease"
• Research Paper # 113314 : "Alzheimer's Disease"

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