Reviewing Cholesterol

Paper Summary:

This essay reviews the article "Altered cholesterol metabolism in Niemann-Pick type C1 mouse brains affects mitochondrial function" published in J. Biol. Chem. This paper provides a short overview of the significance of cholesterol and past published results. After the results of the research from the title article are presented, the further research ideas are given.

From the Paper:

"Cholesterol is a sterols, a member of very important group of lipid alcohols. It can be found in the tissues of all vertebrates, but it only rarely occurs in considerable quantities in higher plants. The most common sterolss in the plant membranes are stigmasterols and b-sitosterols. Their structures are similar to that of cholesterol. The major difference is the structure of the aliphatic side chain bonded to the fused rings. Cholesterol's excess is generally associated with the formation of the plaques in the arteries, which cause them to clog. "

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