Protein Folding

Paper Summary:

This paper discusses the importance of proteins and protein folding to the human body. The paper explains that, during the different stages of protein folding that include primary, secondary, tertiary and sometimes-quaternary structures, the protein becomes susceptible to incorrect folding by binding with other molecules. The paper explores these ?misfoldings?, which may cause diseases such as Alzheimer?s disease, cystic fibrosis, and many cancers. The paper states that researchers continue to try and comprehend the reasons and methods of protein ?misfolding? to further our knowledge of the diseases that are caused by it.

From the Paper:

"Proteins are the biochemical molecules that make up cells, organs and organisms. (1) Like the larger structures, proteins also put themselves together, in a process termed "folding." Protein folding is the process by which a protein assumes its functional shape or conformation. All protein molecules are simple unbranched chains of amino acids, but it is by coiling into a specific three-dimensional shape that they are able to perform their biological function. The proteins fold into either alpha or beta helices with the assistance of chaperon proteins. (1)"

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