Prostate Cancer

Paper Summary:

This paper explains that prostate cancer is the most frequent non-dermatological cancer in men in the United States and it is second to lung cancer as the leading cause of cancer deaths in men. The author points out that, as with other cancers such as breast and colon cancer, which have a familial clustering pattern; prostate cancer cases are believed to be due to a high risk of inherited genetic factors or perhaps even a susceptibility gene. The paper relates that increasing incidence of prostate cancer may be due to better detection, greater awareness on the part of the public of the condition and perhaps even a greater life expectancy with a decrease in the number of competing causes of death rather than a true increase in the prevalence of prostate cancer on the whole.

From the Paper:

"It is interesting to note that maternal cancers also seem to have an affect on the risk of prostate cancers. It is felt that risk of prostate cancer is higher in men with a family history of breast cancer and/or ovarian cancer in a primary relative. This was only reported out in two studies, however, and other studies failed to find any association between family history of female breast cancer and greater risk of prostate cancer. This perhaps may be explained by the questionable increase in prostate cancer in men with BRCA 1 / 2 mutations in the setting of a family history of breast or ovarian cancer. "

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